Effect of combination of gynura procumbens aqueous extract. Merr is a wellknown traditional herb and is widely used for traditional medicine by. Study on antioxidant and antitumor activities of some. Acute toxicity study and wound healing potential of gynura procumbens leaf extract in rats. Gynura procumbens, diabetes mellitus type 1, sperm quality, testosterone introduction. Table 2 shows the antioxidant potential of methanol, aqueous, ethanol and chloroform extract of leaves of t.
Hasseri halim, a siong meng lim, a, c kalavathy ramasamy, a, c and sadia sultan a, b. Abstractthe potential of antioxidant activities of the plant extract gynura procumbens, achyranthes aspera and polygenum tomentosum were studied by using 1, 1diphenyl2picrylhydrazyl dpph. Antioxidant potential in different parts and callus of gynura procumbens and different parts of gynura bicolor vijendren krishnan, 1 syahida ahmad, 1, 2 and maziah mahmood 1, 2 1 institute of biosciences, universiti putra malaysia upm, 43400 serdang, selangor, malaysia. Potassium channel openers and prostacyclin play a crucial role in mediating the vasorelaxant activity of gynura procumbens. Antioxidant potential of gynura 617 antioxidant study of this plant. The aim of this study was to evaluate the antioxidant effect of these two extracts combination. They all belonged to heteropolysaccharides consisted of ara, gal, glc, xyl, gala. Pdf assessment of phytochemicals, antioxidant, and anti. Effects of gynura procumbens leaf extracts on plasma lipid. Chemical and biological investigations of the leaves of. Introduction normal wound healing response begins as soon as the tissue is injured. Evaluation of nutritional value and antioxidative properties. Figure 1 antioxidant potential in different parts and.
Evaluation of total antioxidant activity by phosphomolybdenum method. In vitro antioxidant, antimicrobial and antiproliferative studies of four different extracts of orthosiphon stamineus, gynura procumbens and ficus deltoidea. This herb has displayed potential effect as antihyperglycaemic, antiinflammatory, antihypertensive, and recently, as a profertility agent. Family asteraceae is a medicinal plant commonly found in tropical asia countries such as china, thailand, indonesia, malaysia, and vietnam. Chemical profile and antioxidant activity of gynura bicolor. Jan 04, 2007 antioxidant potential in different parts and callus of gynura procumbens and different parts of gynura bicolor biomed research international, vol. Were really enjoying growing and eating longevity spinach. Gynura procumbens is well known for its various medicinal.
Pdf the ethyl acetate fraction of gynura procumbens. Research on gynura procumbens has also looked at its potential in treating infertility, which can be a complication of diabetes. Merr show that the combination of these two extracts has a potential to be developed into antihyperglycemic agent, through the mechanism of action as an antioxidant. Sep 30, 2015 antioxidant potential in different parts and callus of gynura procumbens and different parts of gynura bicolor. Analysis of biochemical compounds in gynura procumbens. Gynura procumbens standardised extract reduces cholesterol. In this sample the reaction was found to be high indicating high reducing power. The gynura herb is also one of several herbs proven to have antiviral action against herpes simplex. Here, leaf explants were cultivated in ms medium that was supplemented with 0. Potential of gynura procumbens leaves as source of. The f2 has potential for development into phytopharmaceuticals as adjunct therapy for management of hyperlipidemia. Researcharticle antioxidant potential in different parts and callus of gynura procumbens and different parts of gynura bicolor vijendrenkrishnan,1 syahidaahmad,1,2 andmaziahmahmood1,2. Throughout the years, intensive research done on g.
The present study aims to evaluate the relationship between the chemical compositions of both herbs and their antioxidant and antiinflammatory properties using nuclear magnetic resonance nmr metabolomics approach, which. Antioxidant activity and free radicalscavenging capacity of. Akowuah, faculty of pharmaceutical sciences, ucsi university, 56000, kuala lumpur, malaysia. Chemical profile and antioxidant activity of gynura. Gynura procumbens is one of the important medicinal plants in thailand and southeast asia. The contents of the potential antioxidant component of the extract and fractions were also determined. Gynura procumbens, caffeoylquinic acids rich fraction, resin separation, antihyperlipidemic, poloxamer407, antioxidant. Growing longevity spinach gynura procumbens medicinal. Gynura procumbens is well known for its various medicinal properties such as antihyperglycaemic, antihyperlipidaemic, and antiulcerogenic. In a 2008 study, gynura procumbens was found to show an effect on sexual and reproductive function. Phytochemcal screening and in vitro antioxidant activity of. Subfraction 3 had the highest antioxidant activity as well as its total phenolic and flavonoid contents. They all contained uronic acid and protein in their structures. Evaluation of antioxidant properties, cytotoxicity and acute.
The total antioxidant capacity of the extracts was evaluated according to the method described by prieto et al. Tridax procumbens, phytochemical screening, antioxidant activity, antioxidant 1. Chemical and biological investigations of the leaves of gynura procumbens a. Subfraction 3 had the highest antioxidant activity as well as its total. All of various fractions, subfraction 3 showed highest antioxidant activity. In vitro antioxidant, antimicrobial and antiproliferative. Effects of different colored leds on the enhancement of. Gp has been reported in previous studies to possess antihyperlipidaemic, antioxidative, and cardioprotective properties. Longevity spinach is related to but not the same as okinawa spinach, with the scientific name of gynura procumbens, from the family asteraceae. Pdf antioxidant potential in different parts and callus of gynura. Compositae, commonly called sambung nyawa in malaysia, are often eaten raw with rice.
Therefore, experiments were carried out to test the antioxidant potential of g. Gynura procumbens has been consumed for a longtime in tropical regions as a vegetable with health promoting activities. Antioxidant activity was qualitatively and quantitatively determined. Antihypertensive effects of gynura procumbens extract in. The highest extraction yield was obtained from extraction.
Sharif al asad department of applied chemistry and chemical engineering, university of dhaka, dhaka, bangladesh key words. The present study determined nutritional value in various parameters such as moisture content, carbohydrate, protein, lipid as standard methods and evaluated the antioxidative properties of the medicinal plant gynura procumbens extract by hydroxyl scavenging activity, ferrous ionchelating activity and inhibition of lipid peroxidation. Potential of gynura procumbens leaves as source of flavonoid. The use of lightemitting diodes leds is the best option due to their potential role as elicitors of secondary metabolite production in many plant models.
To study the antidiabetic activity of gynura procumbens leaves to manage diabetes. The gynura herb gynura procumbens is a potent antiviral against herpes simplex virus 1 and hsv2 according to human and laboratory research. Plants from gynura family was used in this study, namely, gynura procumbens and gynura bicolor. The current experiments show that the medicinal properties of g. Pdf antioxidant potential in different parts and callus. Gynura procumbens, ethanol leaf extract, acute toxicity, liver function test, renal function test, wound healing, histology. Antioxidant potential in different parts and callus of gynura procumbens and different parts of gynura bicolor figure 1 total antioxidant content of g. Wound healing is the process of repair that follows injury to the skin and other soft tissues. Effect of cadmium and copper exposure on growth, secondary.
The methanol extract was then fractionated into chloroform, ethyl acetate, nbutanol, and aqueous fractions using a separating funnel. Due to that, the 1,1diphenyl2picrylhydrazyl dpph, ferric reducing antioxidant potential frap and antibacterial activities was also found to be reduced by the combined treatments. To study the potential toxicity for many of the biochemical compounds in gynura procumbens leaves. Traditionally, it is widely used in many different countries for the treatment of a wide variety of health ailments such as kidney discomfort, rheumatism, diabetes mellitus, constipation, and hypertension. This herb, which is scientifically known as gynura procumbens gp, is a shrub plant that widely grows within the southeast asia region. This study aimed to assess whether feg produced synergistic effect with 5 fu and cisp and to evaluate its regulation on proliferation, cell cycle, and cell death induction on widr colon. We investigated phenolic antioxidants that were fractionated from the crude extract of g. Antioxidant potential in different parts and callus of. It is usually used as a traditional medicine for the treatment of inflammation, herpes simplex virus, rashes, fever, rheumatism, kidney disease, migraines, constipation, diabetes mellitus, cancer and hypertension. The antiherpetic results of the treated groups 1 and decreasing from the vast potential medical applications of g. Caffeoylquinic acids rich versus poor fractions of gynura. The antioxidant and free radicalscavenging activity were measured by 1,1diphenyl2picrylhydrazyl dpph, 2,2azinobis3ethylbenzthiazoline6sulfonic acid abts and phosphomolybdenum methods.
The percent inhibition of blood vessel on 98 cam treated with various extracts and fractions of gynura segetum leaf table 4. Assessment of phytochemicals, antioxidant, and antiinflammatory potential of boerhavia procumbens banks ex roxb. Antioxidant activity and free radicalscavenging capacity. Their comparative antihyperlipidemic and antioxidant potential. Figure 4 antioxidant potential in different parts and. Traditionally, it is widely used in many different countries for the treatment.
Antioxidant potential in different parts and callus of gynura procumbens and different parts of gynura bicolor figure 4 total flavonoid content of g. The accumulation of heavy metal also was found to be. Research article antioxidant potential in different parts and callus of gynura procumbens and different parts of gynura bicolor vijendren krishnan,1 syahida ahmad,1,2 and maziah mahmood1,2 1 institute of biosciences, universiti putra malaysia upm, 43400 serdang, selangor, malaysia faculty of biotechnology and biomolecular sciences, universiti. In this study, the absorbance of ascorbic acid was treated as 100% antioxidant potential. Antioxidant properties of gynura procumbens extracts and their. Their physicochemical properties and antioxidant activities were determined. Gynura procumbens which is locally known as sambung nyawa in malay and feng wei jian in chinese, belongs to the botanical family of compositae. In this analysis, ascorbic acid vitamin c was used as. Research article antioxidant potential in different parts and callus of gynura procumbens and different parts of gynura bicolor. The extraction conditions were optimized and the total phenolic content of g. Antioxidant potential in different parts and callus of gynura. Pdf antioxidant potential of gynura procumbens researchgate. Murugesu k1, murugaiyah v2, saghir sam1, asmawi mz2, sadikun a1. In frap assay, reducing power was not detected in g.
Research article antioxidant potential in different parts. Four new polysaccharides were fractionated from gynura procumbens leaves. This study was aimed to determine the effect of standardised 80% ethanol extract of gp on lipid profiles and oxidative status of hypercholesterolemic rats. Acute toxicity study and wound healing potential of gynura. The results of this study reveal that tridax procumbens leaf extract possess significant antioxidant properties and could be exploited as source of antioxidant additives. Several nonenzymatic antioxidants methods were utilized to study the antioxidant capacity, which. Gynura herb fights herpes simplex infections journal of. Extracts on antiproliferative activity and its associated morphological changes of human. In asian countries, medicinal plants are still commonly used as complementary or alternative medicine to treat cancer.
Research article antioxidant potential in different. The present study aims to evaluate the relationship between the chemical compositions of both herbs and their antioxidant and antiinflammatory properties using nuclear magnetic resonance nmr metabolomics approach, which is being. Evaluation of antioxidant properties, cytotoxicity and. Several nonenzymatic antioxidants methods were utilized to study the antioxidant capacity, which include. The methanol extract was prepared from the dried leaves using a soxhlet apparatus. Physicochemical properties and antioxidant activities of. In vitro antioxidant, antimicrobial and antiproliferative studies of four different extracts of orthosiphon stamineus, gynura procumbens and ficus deltoidea kamran ashraf, a, b. Molecules free fulltext effect of cadmium and copper. Gynura procumbens, antimicrobial activity, cytotoxicity, antioxidant property, stigmasterol. Oho tpaaviuviohho vic110j1b30bajiocb neqehv1 nvrxopaak1,1, cblnvr, 3aoonebahnn noqek, mvrrperm, 3anopob, rnnept0hvrv1, caxaphoro al1aoeta paka perry, 1980. In the current study, the antioxidant potency of g. Vijendren krishnan institute of biosciences, universiti putra malaysia upm, 43400 serdang, selangor, malaysia.
Gynura procumbens and cleome gynandra are two herbs commonly used in malaysia to treat various ailments and are also consumed as salads ulam and vegetables. Research article antioxidant potential in different parts and callus of gynura procumbens and different parts of gynura bicolor vijendrenkrishnan, 1 syahidaahmad, 1,2 andmaziahmahmood 1,2 institute of biosciences, universiti putra malaysia upm, serdang, selangor, malaysia. Research article antioxidant potential in different parts and. In this study, chemical profile and antioxidant activity of g. Effect of gynura procumbens extracts on antiproliferative. Gynura have been found in different studies to contain coumarins, anthocyanins pyrrolizidine alkaloids, spirostanol and several anthocyanins. Lets take a look at the science and some of the active compounds for this antiviral herb. Folinciocalteu and aluminum chloride colorimetric assay were used to determine the tpc and tfc of gynura divaricata leaf extracts at different temperatures. Evaluation of phytochemical composition and antibacterial. Key active compounds from gynura procumbens were purified using multiple steps.
Introduction medicinal plants have been used for centuries before the. Postmenopausal pm spraguedawley rats were ovariectomised and fed. Antioxidant potential in different parts and callus of gynura procumbens and different parts of gynura bicolor. Caffeoylquinic acids rich versus poor fractions of gynura procumbens. Effects of gynura procumbens leaf extracts on plasma lipid peroxidation and total antioxidant status in ccl4treated rats authors.